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KMID : 1038120190520050497
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Clinical Endoscopy
2019 Volume.52 No. 5 p.497 ~ p.501
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New Diagnostic Approach for Esophageal Squamous Cell Neoplasms Using Linked Color Imaging and Blue Laser Imaging Combined with Iodine Staining
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Tsunoda Masato
Miura Yoshimasa
Osawa Hiroyuki
Khurelbaatar Tsevelnorov
Sakaguchi Mio
Fukuda Hisashi
Lefor Alan Kawarai
Yamamoto Hironori
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Abstract
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A 62-year-old man with a flat early esophageal cancer was referred for endoscopic treatment. White light imaging revealed a pale red lesion, whereas linked color imaging (LCI) and blue laser imaging (BLI) yielded purple and brown images, respectively. Iodine staining demonstrated a large unstained area with a homogenous but very weak pink-color sign. This area appeared more clearly as purple and green on LCI and BLI, respectively; however, a different colored portion was observed at the 4 o’clock position inside the iodineunstained area. Histopathology findings of the resected specimen revealed squamous intraepithelial neoplasia at the 4 o’clock position and an esophageal squamous cell carcinoma in the remaining iodine-unstained area. LCI and BLI combined with iodine staining produce characteristic images that overcomes the pink-color sign, reflecting the histological features of a flat esophageal neoplasm. This new method is useful for detailed evaluation of early flat squamous cell neoplasms.
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KEYWORD
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Early esophageal cancer, Image enhanced endoscopy, Linked color imaging, Blue laser imaging, Iodine staining
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